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The antibody against ALAS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ALAS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09473A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALAS2 |
| Target Synonyms | ASB; ANH1; XLSA; ALASE; XLDPP; XLEPP; ALAS-E; SIDBA1; ALAS2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, Mouse liver, Mouse lung, Mouse spleen | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 50-320 of human ALAS2 (NP_001033057.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P22557 | Immunogen Sequence |
Uniprot Id
P22557
Target Species
Human
Target Name
ALAS2
Target Full Name
5-aminolevulinate synthase, erythroid-specific, mitochondrial
Target Involvement
Anemia, sideroblastic, 1 (SIDBA1); Erythropoietic protoporphyria, X-linked dominant (XLDPT)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II pyridoxal-phosphate-dependent aminotransferase family
Target Tissue Specificity
Erythroid specific.
Target Research Area
Cancer
Target Synonyms
5 @aminolevulinate synthase erythroid specific; 5 aminolevulinate synthase 2; 5 aminolevulinate synthase 5 aminolevulinate synthase 2; 5 aminolevulinate synthase erythroid specific mitochondrial; 5 aminolevulinic acid synthase 2; 5 aminolevulinic acid synthase; 5-aminolevulinate synthase; 5-aminolevulinic acid synthase 2; Alas 2; ALAS; ALAS E; ALAS; erythroid; ALAS-E; Alas2; ALASE; Aminolevulinate delta synthase 2; Aminolevulinic acid synthase 2; erythroid; ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate synthase 2; Delta aminolevulinate synthase; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2; Erythroid specific ALAS; erythroid-specific; FLJ93603; HEM0_HUMAN; mitochondrial; OTTHUMP00000023388; OTTHUMP00000023389; OTTMUSP00000020679; RP23-338A17.1; SIDBA1; XLDPP; XLEPP; XLSA
Target Background
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
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