Rabbit anti-Human ALDH1A3 Polyclonal Antibody

The antibody against ALDH1A3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ALDH1A3 (NP_000684.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11389A

Number

Cat.No	ADA-11389A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ALDH1A3
Target Synonyms	ALDH6; MCOP8; RALDH3; ALDH1A6; ALDH1A3	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse pancreas	Application	ELISA, WB

Cat.No

ADA-11389A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ALDH1A3

Target Synonyms

ALDH6; MCOP8; RALDH3; ALDH1A6; ALDH1A3

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse pancreas

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ALDH1A3 (NP_000684.2).	Target Species	Human
Immunogen Sequence	MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT	Uniprot ID	P47895

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human ALDH1A3 (NP_000684.2).

Target Species

Human

Immunogen Sequence

MATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRT

Uniprot ID

P47895

Background Information

Uniprot Id

P47895
Target Species

Human
Target Name

ALDH1A3
Target Full Name

Retinaldehyde dehydrogenase 3
Target Function

NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid. Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde. Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region.
Target Involvement

Microphthalmia, isolated, 8 (MCOP8)
Target Subcellular Location

Cytoplasm.
Target Protein Families

Aldehyde dehydrogenase family
Target Tissue Specificity

Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Target Research Area

Others
Target Synonyms

Acetaldehyde dehydrogenase 6; AL1A3_HUMAN; Aldehyde dehydrogenase 1A3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; Aldh1a3; ALDH1A6; ALDH6; RALDH 3; Retinaldehyde dehydrogenase 3; V1
Target Background

This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.

Rabbit anti-Human ALDH1A3 Polyclonal Antibody

Specifications

Immunogen Information

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