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The antibody against ALDH1A3 was raised in rabbit using the Recombinant Human Aldehyde dehydrogenase family 1 member A3 protein (2-210AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against ALDH1A3 was raised in rabbit using the Recombinant Human Aldehyde dehydrogenase family 1 member A3 protein (2-210AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
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| Cat.No | ADC-14089A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALDH1A3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | FITC conjugated |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Aldehyde dehydrogenase family 1 member A3 protein (2-210AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P47895 |
Uniprot Id
P47895
Target Species
Human
Target Name
ALDH1A3
Target Full Name
Retinaldehyde dehydrogenase 3
Target Function
NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid. Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde. Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region.
Target Involvement
Microphthalmia, isolated, 8 (MCOP8)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Aldehyde dehydrogenase family
Target Tissue Specificity
Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.
Target Research Area
Others
Target Synonyms
Acetaldehyde dehydrogenase 6; AL1A3_HUMAN; Aldehyde dehydrogenase 1A3; Aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; Aldh1a3; ALDH1A6; ALDH6; RALDH 3; Retinaldehyde dehydrogenase 3; V1
Target Background
This gene encodes an aldehyde dehydrogenase enzyme that uses retinal as a substrate. Mutations in this gene have been associated with microphthalmia, isolated 8, and expression changes have also been detected in tumor cells. Alternative splicing results in multiple transcript variants.
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