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The antibody against ALDH1B1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against ALDH1B1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-11239A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALDH1B1 |
| Target Synonyms | ALDH5; ALDHX; ALDH1B1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, HepG2, Mouse testis, Rat liver, SKOV3, SW620 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 278-517 of human ALDH1B1 (NP_000683.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P30837 | Immunogen Sequence |
Uniprot Id
P30837
Target Species
Human
Target Name
ALDH1B1
Target Full Name
Aldehyde dehydrogenase X, mitochondrial
Target Function
ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation.
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Aldehyde dehydrogenase family
Target Tissue Specificity
Liver, testis and to a lesser extent in brain.
Target Research Area
Metabolism
Target Synonyms
Acetaldehyde dehydrogenase 5; AL1B1_HUMAN; Aldehyde dehydrogenase 1 family; member B1; Aldehyde dehydrogenase 1B1; Aldehyde dehydrogenase 5; Aldehyde dehydrogenase family 1 member B1; Aldehyde dehydrogenase X; Aldehyde dehydrogenase X mitochondrial; ALDH class 2; Aldh1b1; ALDH5; ALDHX; MGC2230; Mitochondrial aldehyde dehydrogenase X; mitochondrial; OTTHUMP00000021399
Target Background
This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. This gene does not contain introns in the coding sequence. The variation of this locus may affect the development of alcohol-related problems.
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