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Rabbit anti-Human ALDH1L1 Monoclonal Antibody

The antibody against ALDH1L1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human ALDH1L1 (O75891) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-13981A

The antibody against ALDH1L1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human ALDH1L1 (O75891) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-13981A ClonalityMonoclonal
Host SpeciesRabbitTarget NameALDH1L1
Target SynonymsFDH; FTHFD; 10-fTHF; 10-FTHFDH; ALDH1L1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse liver, Rat liverApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human ALDH1L1 (O75891).Target SpeciesHuman
Immunogen SequenceVRLIAEGKAPRLPQPEEGATYEGIQKKETAKINWDQPAEAIHNWIRGNDKVPGAWTEACEQKLTFFNSTLNTSGLVPEGDALPIPGAHRPGVVTKAGLILFGNDDKMLLVKNIQLEDGKMIUniprot IDO75891
Background Information
  • Uniprot Id

    O75891

  • Target Species

    Human

  • Target Name

    ALDH1L1

  • Target Full Name

    Cytosolic 10-formyltetrahydrofolate dehydrogenase

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    GART family; Aldehyde dehydrogenase family, ALDH1L subfamily

  • Target Tissue Specificity

    Highly expressed in liver, pancreas and kidney.

  • Target Synonyms

    10 formyltetrahydrofolate dehydrogenase; 10 FTHFDH; 10-formyltetrahydrofolate dehydrogenase; 10-FTHFDH; AL1L1_HUMAN; Aldehyde dehydrogenase 1 family member L1; Aldehyde dehydrogenase family 1 member L1; aldh1l1; Cytosolic 10-formyltetrahydrofolate dehydrogenase; DKFZp781N0997; EC 1.5.1.6; FDH; formyltetrahydrofolate dehydrogenase; FTHFD; OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700; OTTHUMP00000222724

  • Target Background

    The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants.

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