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The antibody against ALDH1L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ALDH1L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05629A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALDH1L2 |
| Target Synonyms | mtFDH; ALDH1L2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse pancreas, Rat liver, Rat pancreas | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 280-480 of human ALDH1L2 (NP_001029345.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q3SY69 | Immunogen Sequence |
Uniprot Id
Q3SY69
Target Species
Human
Target Name
ALDH1L2
Target Full Name
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
Target Subcellular Location
Mitochondrion.
Target Protein Families
GART family; Aldehyde dehydrogenase family, ALDH1L subfamily
Target Tissue Specificity
Highly expressed in pancreas, heart, brain and skeletal muscle.
Target Synonyms
10 formyltetrahydrofolate dehydrogenase ALDH1L2; 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, MITOCHONDRIAL; AL1L2_HUMAN; Aldehyde dehydrogenase 1 family, member L2; Aldehyde dehydrogenase family 1 member L2; Aldehyde dehydrogenase family 1 member L2, mitochondrial; ALDH1L2; Mitochondrial 10 formyltetrahydrofolate dehydrogenase; Mitochondrial 10 FTHFDH; mtFDH; Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
Target Background
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
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