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The antibody against ALDH1L2 was raised in rabbit using the Recombinant Human Mitochondrial 10-formyltetrahydrofolate dehydrogenase protein (263-562AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ALDH1L2 was raised in rabbit using the Recombinant Human Mitochondrial 10-formyltetrahydrofolate dehydrogenase protein (263-562AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human pancreatic tissue using ALDH1L2 Antibody at dilution of 1:100
| Cat.No | ADC-20144A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALDH1L2 |
| Target Synonyms | 10 formyltetrahydrofolate dehydrogenase ALDH1L2 antibody; 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, member L2 antibody; Aldehyde dehydrogenase family 1 member L2 antibody; Aldehyde dehydrogenase family 1 member L2, MITOCHONDRIAL antibody; AL1L2_HUMAN antibody; Aldehyde dehydrogenase 1 family | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Mitochondrial 10-formyltetrahydrofolate dehydrogenase protein (263-562AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q3SY69 |
Uniprot Id
Q3SY69
Target Species
Human
Target Name
ALDH1L2
Target Full Name
Mitochondrial 10-formyltetrahydrofolate dehydrogenase
Target Subcellular Location
Mitochondrion.
Target Protein Families
GART family; Aldehyde dehydrogenase family, ALDH1L subfamily
Target Tissue Specificity
Highly expressed in pancreas, heart, brain and skeletal muscle.
Target Synonyms
10 formyltetrahydrofolate dehydrogenase ALDH1L2; 10-FORMYLTETRAHYDROFOLATE DEHYDROGENASE, MITOCHONDRIAL; AL1L2_HUMAN; Aldehyde dehydrogenase 1 family, member L2; Aldehyde dehydrogenase family 1 member L2; Aldehyde dehydrogenase family 1 member L2, mitochondrial; ALDH1L2; Mitochondrial 10 formyltetrahydrofolate dehydrogenase; Mitochondrial 10 FTHFDH; mtFDH; Probable 10-formyltetrahydrofolate dehydrogenase ALDH1L2
Target Background
This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.
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