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The antibody against ALDH6A1 was raised in rabbit using the Fusion protein of Human ALDH6A1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ALDH6A1 was raised in rabbit using the Fusion protein of Human ALDH6A1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-30993A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALDH6A1 |
| Target Synonyms | 1110038I05Rik antibody; AI314632 antibody; Aldehyde dehydrogenase 6 family member A1 antibody; Aldehyde dehydrogenase family 6 member A1 antibody; Aldehyde dehydrogenase family 6 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human ALDH6A1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q02252 |
Uniprot Id
Q02252
Target Species
Human
Target Name
ALDH6A1
Target Full Name
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase [acylating], mitochondrial
Target Function
Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA.
Target Involvement
Methylmalonate semialdehyde dehydrogenase deficiency (MMSDHD)
Target Subcellular Location
Mitochondrion.
Target Protein Families
Aldehyde dehydrogenase family
Target Synonyms
MMSDH; MMSADHA; ALDH6A1
Target Background
This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants.
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