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The antibody against ALG1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 215-464 of human ALG1 (NP_061982.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ALG1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 215-464 of human ALG1 (NP_061982.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01926A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALG1 |
| Target Synonyms | HMT1; MT-1; CDG1K; HMAT1; HMT-1; Mat-1; hMat-1; ALG1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, HepG2, Mouse liver, Mouse ovary, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 215-464 of human ALG1 (NP_061982.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9BT22 | Immunogen Sequence |
Uniprot Id
Q9BT22
Target Species
Human
Target Name
ALG1
Target Full Name
Chitobiosyldiphosphodolichol beta-mannosyltransferase
Target Function
Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.
Target Involvement
Congenital disorder of glycosylation 1K (CDG1K)
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase group 1 family, Glycosyltransferase 33 subfamily
Target Synonyms
4-mannosyltransferase; Alg1; ALG1_HUMAN; asparagine-linked glycosylation 1 homolog (yeast; beta-1,4-mannosyltransferase); asparagine-linked glycosylation 1; beta-1,4-mannosyltransferase homolog (S. cerevisiae); Asparagine-linked glycosylation protein 1 homolog; Beta 1 4 mannosyltransferase; Beta-1; CDG1K; Chitobiosyldiphosphodolichol beta-mannosyltransferase; GDP Man GlcNAc2 PP dolichol mannosyltransferase; GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase; GDP-mannose-dolichol diphosphochitobiose mannosyltransferase; Hmat-1; HMAT1; HMT 1; HMT1; Mannosyltransferase 1; Mannosyltransferase-1; MT 1; MT-1; MT1
Target Background
The enzyme encoded by this gene catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. This gene is mutated in congenital disorder of glycosylation type Ik.
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