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Rabbit anti-Human ALPP Polyclonal Antibody

The antibody against ALPP was raised in rabbit using the Recombinant Human Alkaline phosphatase, placental type protein (260-520AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IP.

ADC-44457A

The antibody against ALPP was raised in rabbit using the Recombinant Human Alkaline phosphatase, placental type protein (260-520AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IP.

$299.00

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Specifications


Cat.No ADC-44457A ClonalityPolyclonal
Host SpeciesRabbitTarget NameALPP
Target SynonymsALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB, IP
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Alkaline phosphatase, placental type protein (260-520AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP05187
Background Information
  • Uniprot Id

    P05187

  • Target Species

    Human

  • Target Name

    ALPP

  • Target Full Name

    Alkaline phosphatase, placental type

  • Target Function

    Alkaline phosphatase that can hydrolyze various phosphate compounds.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    Alkaline phosphatase family

  • Target Tissue Specificity

    Detected in placenta (at protein level).

  • Target Research Area

    Tags & Cell Markers

  • Target Synonyms

    ALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1

  • Target Background

    The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. One of the main sources of this enzyme is the liver, and thus, it's one of several indicators of liver injury in different clinical conditions. In pregnant women, this protein is primarily expressed in placental and endometrial tissue, however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.

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