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Rabbit anti-Human AMN Polyclonal Antibody

The antibody against AMN was raised in rabbit using the Recombinant Human Protein amnionless protein (25-163AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-04590A

The antibody against AMN was raised in rabbit using the Recombinant Human Protein amnionless protein (25-163AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-04590A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAMN
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Protein amnionless protein (25-163AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9BXJ7
Background Information
  • Uniprot Id

    Q9BXJ7

  • Target Species

    Human

  • Target Name

    AMN

  • Target Full Name

    Protein amnionless

  • Target Function

    Membrane-bound component of the endocytic receptor formed by AMN and CUBN. Required for normal CUBN glycosylation and trafficking to the cell surface. The complex formed by AMN and CUBN is required for efficient absorption of vitamin B12. Required for normal CUBN-mediated protein transport in the kidney (Probable).

  • Target Involvement

    Recessive hereditary megaloblastic anemia 1 (RH-MGA1)

  • Target Subcellular Location

    [Isoform 1]: Apical cell membrane; Single-pass type I membrane protein. Cell membrane; Single-pass type I membrane protein. Endosome membrane. Membrane, coated pit.; [Soluble protein amnionless]: Secreted.

  • Target Tissue Specificity

    Detected in proximal tubules in the kidney cortex (at protein level). Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and per

  • Target Synonyms

    5033428N14Rik; amn; Amnion associated transmembrane protein; Amnionless; Amnionless homolog; AMNLS_HUMAN; AV002116; PRO1028; Protein amnionless; Type I transmembrane protein; UNQ513/PRO1028; Visceral endoderm specific type 1 transmembrane protein

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