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The antibody against AMPD1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human AMPD1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
The antibody against AMPD1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human AMPD1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.
$167.00
| Cat.No | ADC-35617A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AMPD1 |
| Target Synonyms | AMPD1AMP deaminase 1 antibody; EC 3.5.4.6 antibody; AMP deaminase isoform M antibody; Myoadenylate deaminase antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human AMPD1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23109 |
Uniprot Id
P23109
Target Species
Human
Target Name
AMPD1
Target Full Name
AMP deaminase 1
Target Function
AMP deaminase plays a critical role in energy metabolism.
Target Involvement
Myopathy due to myoadenylate deaminase deficiency (MMDD)
Target Protein Families
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
Target Synonyms
AMPD1AMP deaminase 1; EC 3.5.4.6; AMP deaminase isoform M; Myoadenylate deaminase
Target Background
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
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