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The antibody against AMPD3 was raised in rabbit using the Recombinant Human AMP deaminase 3 protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against AMPD3 was raised in rabbit using the Recombinant Human AMP deaminase 3 protein (1-260AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
| Cat.No | ADC-44438A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AMPD3 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human AMP deaminase 3 protein (1-260AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q01432 |
Uniprot Id
Q01432
Target Species
Human
Target Name
AMPD3
Target Full Name
AMP deaminase 3
Target Function
AMP deaminase plays a critical role in energy metabolism.
Target Involvement
Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)
Target Protein Families
Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family
Target Synonyms
AMPD3
Target Background
This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
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