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The antibody against AMT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 107-386 of human AMT (NP_001158184.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against AMT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 107-386 of human AMT (NP_001158184.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-00866A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AMT |
| Target Synonyms | GCE; NKH; GCST; GCVT; AMT | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 22Rv1, LO2, Mouse brain, Mouse pancreas, Rat liver, SW620 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 107-386 of human AMT (NP_001158184.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P48728 | Immunogen Sequence |
Uniprot Id
P48728
Target Species
Human
Target Name
AMT
Target Full Name
Aminomethyltransferase, mitochondrial
Target Function
The glycine cleavage system catalyzes the degradation of glycine.
Target Involvement
Non-ketotic hyperglycinemia (NKH)
Target Subcellular Location
Mitochondrion.
Target Protein Families
GcvT family
Target Synonyms
Aminomethyltransferase (glycine cleavage system protein T) ; Aminomethyltransferase; AMT; GCE ; GCST ; GCST_HUMAN; GCVT; Glycine cleavage system T protein; mitochondrial; NKH
Target Background
This gene encodes one of four critical components of the glycine cleavage system. Mutations in this gene have been associated with glycine encephalopathy. Multiple transcript variants encoding different isoforms have been found for this gene.
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