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Rabbit anti-Human ANXA9 Polyclonal Antibody

The antibody against ANXA9 was raised in rabbit using the Recombinant Human Annexin A9 protein (8-345AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-49488A

The antibody against ANXA9 was raised in rabbit using the Recombinant Human Annexin A9 protein (8-345AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-49488A ClonalityPolyclonal
Host SpeciesRabbitTarget NameANXA9
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Annexin A9 protein (8-345AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO76027
Background Information
  • Uniprot Id

    O76027

  • Target Species

    Human

  • Target Name

    ANXA9

  • Target Full Name

    Annexin A9

  • Target Function

    Low affinity receptor for acetylcholine known to be targeted by disease-causing pemphigus vulgaris antibodies in keratinocytes.

  • Target Protein Families

    Annexin family

  • Target Tissue Specificity

    Expressed in the stratified squamous skin epithelium, but not in epithelia of other types (at protein level).

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    annexin 31; annexin 31; formerly; Annexin A9; Annexin XXXI; Annexin-31; Annexin-9; ANX31; ANX31; formerly; ANXA9; ANXA9_HUMAN; Pemphaxin

  • Target Background

    The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. This gene encodes a divergent member of the annexin protein family in which all four homologous type II calcium-binding sites in the conserved tetrad core contain amino acid substitutions that ablate their function. However, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.

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