Rabbit anti-Human APRT Polyclonal Antibody

The antibody against APRT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09690A

Number

Cat.No	ADA-09690A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	APRT
Target Synonyms	AMP; APRTD; APRT	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T	Application	ELISA, WB

Cat.No

ADA-09690A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

APRT

Target Synonyms

AMP; APRTD; APRT

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1).	Target Species	Human
Immunogen Sequence	MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE	Uniprot ID	P07741

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human APRT (NP_000476.1).

Target Species

Human

Immunogen Sequence

MADSELQLVEQRIRSFPDFPTPGVVFRDISPVLKDPASFRAAIGLLARHLKATHGGRIDYIAGLDSRGFLFGPSLAQELGLGCVLIRKRGKLPGPTLWASYSLEYGKAELEIQKDALEPGQRVVVVDDLLATGGTMNAACELLGRLQAEVLECVSLVELTSLKGREKLAPVPFFSLLQYE

Uniprot ID

P07741

Background Information

Uniprot Id

P07741
Target Species

Human
Target Name

APRT
Target Full Name

Adenine phosphoribosyltransferase
Target Function

Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
Target Involvement

Adenine phosphoribosyltransferase deficiency (APRTD)
Target Subcellular Location

Cytoplasm.
Target Protein Families

Purine/pyrimidine phosphoribosyltransferase family
Target Research Area

Signal Transduction
Target Synonyms

Adenine phosphoribosyltransferase; AMP; AMP diphosphorylase; AMP pyrophosphorylase; APRT; APT_HUMAN; DKFZp686D13177; MGC125856; MGC125857; MGC129961; Transphosphoribosidase
Target Background

Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2, 8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human APRT Polyclonal Antibody

Specifications

Immunogen Information

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