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The antibody against AQP5 was raised in rabbit using the Synthetic peptide of Human AQP5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against AQP5 was raised in rabbit using the Synthetic peptide of Human AQP5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-28779A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AQP5 |
| Target Synonyms | AQP 5 antibody; AQP-5 antibody; AQP5 antibody; AQP5_HUMAN antibody; Aquaporin 5 antibody; Aquaporin-5 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human AQP5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P55064 |
Uniprot Id
P55064
Target Species
Human
Target Name
AQP5
Target Full Name
Aquaporin-5
Target Function
Forms a water-specific channel. Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands.
Target Involvement
Keratoderma, palmoplantar, Bothnian type (PPKB)
Target Subcellular Location
Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein.
Target Protein Families
MIP/aquaporin (TC 1.A.8) family
Target Tissue Specificity
Detected in skin eccrine sweat glands, at the apical cell membrane and at intercellular canaliculi (at protein level).
Target Research Area
Transport, Signal Transduction
Target Synonyms
AQP 5; AQP-5; AQP5; AQP5_HUMAN; Aquaporin 5; Aquaporin-5
Target Background
Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13.
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