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The antibody against ARF4 was raised in rabbit using the Recombinant Human ADP-ribosylation factor 4 protein (1-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ARF4 was raised in rabbit using the Recombinant Human ADP-ribosylation factor 4 protein (1-180AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using ARF4 Antibody at dilution of 1:1002
| Cat.No | ADC-46307A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARF4 |
| Target Synonyms | ADP ribosylation factor 2 antibody; ADP ribosylation factor 4 antibody; ADP-ribosylation factor 4 antibody; ARF2 antibody; ARF4 antibody; ARF4_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human ADP-ribosylation factor 4 protein (1-180AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P18085 |
Uniprot Id
P18085
Target Species
Human
Target Name
ARF4
Target Full Name
ADP-ribosylation factor 4
Target Function
GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
Target Subcellular Location
Golgi apparatus. Membrane; Lipid-anchor.
Target Protein Families
Small GTPase superfamily, Arf family
Target Research Area
Transport
Target Synonyms
ADP ribosylation factor 2 ; ADP ribosylation factor 4; ADP-ribosylation factor 4; ARF2; ARF4; ARF4_HUMAN
Target Background
This gene is a member of the human ARF gene family whose members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 5 ARF proteins and 11 ARF-like proteins and constitute one family of the RAS superfamily. The ARF proteins are categorized as class I, class II and class III; this gene is a class II member. The members of each class share a common gene organization. The ARF4 gene spans approximately 12kb and contains six exons and five introns. This gene is the most divergent member of the human ARFs. Conflicting map positions at 3p14 or 3p21 have been reported for this gene.
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