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The antibody against ARFIP1 was raised in rabbit using the Synthesized peptide derived from internal of Human ARFIP1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
The antibody against ARFIP1 was raised in rabbit using the Synthesized peptide derived from internal of Human ARFIP1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IF.
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Western blot analysis of extracts from Jurkat cells, using ARFIP1 antibody.
Immunofluorescence analysis of A549 cells, using ARFIP1 antibody.2
| Cat.No | ADC-41472A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARFIP1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human ARFIP1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P53367 |
Uniprot Id
P53367
Target Species
Human
Target Name
ARFIP1
Target Full Name
Arfaptin-1
Target Function
Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network. Mechanisitically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold. Once the granule precursor has been completely loaded, active PRKD1 phosphorylates ARFIP1 and releases it from ARFs. In turn, ARFs induce fission. Through this mechanism, ensures proper secretory granule formation at the Golgi of pancreatic beta cells.
Target Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Target Tissue Specificity
Ubiquitously expressed. Higher levels in liver, pancreas, placenta, skeletal muscle and heart.
Target Synonyms
ADP ribosylation factor interacting protein 1; ADP-ribosylation factor-interacting protein 1; Arfaptin; Arfaptin-1; ARFIP 1; Arfip1; ARFP1_HUMAN; HSU52521; MGC117369
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