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The antibody against ARHGAP10 was raised in rabbit using the Recombinant Human Rho GTPase-activating protein 10 protein (542-744AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ARHGAP10 was raised in rabbit using the Recombinant Human Rho GTPase-activating protein 10 protein (542-744AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human lung cancer using ARHGAP10 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using ARHGAP10 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-16125A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARHGAP10 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Rho GTPase-activating protein 10 protein (542-744AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A1A4S6 |
Uniprot Id
A1A4S6
Target Species
Human
Target Name
ARHGAP10
Target Full Name
Rho GTPase-activating protein 10
Target Function
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cell membrane.
Target Tissue Specificity
High levels of expression in heart and skeletal muscle.
Target Synonyms
Arhgap10; Graf-related protein 2; GRAF2; GTPase regulator associated with focal adhesion kinase 2; PS GAP; PSGAP; RHG10_HUMAN; Rho GTPase-activating protein 10; Rho-type GTPase-activating protein 10
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