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The antibody against ARHGAP10 was raised in rabbit using the Human ARHGAP10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against ARHGAP10 was raised in rabbit using the Human ARHGAP10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-49219A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARHGAP10 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human ARHGAP10 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A1A4S6 |
Uniprot Id
A1A4S6
Target Species
Human
Target Name
ARHGAP10
Target Full Name
Rho GTPase-activating protein 10
Target Function
GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death.
Target Subcellular Location
Cytoplasm. Cytoplasm, perinuclear region. Cell membrane.
Target Tissue Specificity
High levels of expression in heart and skeletal muscle.
Target Synonyms
Arhgap10; Graf-related protein 2; GRAF2; GTPase regulator associated with focal adhesion kinase 2; PS GAP; PSGAP; RHG10_HUMAN; Rho GTPase-activating protein 10; Rho-type GTPase-activating protein 10
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