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Rabbit anti-Human ARL4C Polyclonal Antibody

The antibody against ARL4C was raised in rabbit using the Recombinant Human ADP-ribosylation factor-like protein 4C protein (2-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-22224A

The antibody against ARL4C was raised in rabbit using the Recombinant Human ADP-ribosylation factor-like protein 4C protein (2-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-22224A ClonalityPolyclonal
Host SpeciesRabbitTarget NameARL4C
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human ADP-ribosylation factor-like protein 4C protein (2-192AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP56559
Background Information
  • Uniprot Id

    P56559

  • Target Species

    Human

  • Target Name

    ARL4C

  • Target Full Name

    ADP-ribosylation factor-like protein 4C

  • Target Function

    Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process.

  • Target Subcellular Location

    Cell projection, filopodium. Cell membrane. Cytoplasm.

  • Target Protein Families

    Small GTPase superfamily, Arf family

  • Target Tissue Specificity

    Expressed in several tumor cell lines (at protein level). Expressed in lung, brain, leukocytes and placenta.

  • Target Synonyms

    ADP ribosylation factor like 4C; ADP ribosylation factor like 7; ADP-ribosylation factor-like protein 4C; ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK; Arl4c; ARL4C_HUMAN; ARL7; LAK

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