Rabbit anti-Human ARPC1A Polyclonal Antibody

Uniprot Id

Q92747

Target Species

Human

Target Name

ARPC1A

Target Full Name

Actin-related protein 2/3 complex subunit 1A

Target Function

Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.

Target Subcellular Location

Cytoplasm, cytoskeleton. Nucleus.

Target Protein Families

WD repeat ARPC1 family

Target Synonyms

Actin binding protein (Schizosaccharomyces pombe sop2 like); Actin related protein 2/3 complex subunit 1A 41kDa; Actin-related protein 2/3 complex subunit 1A; ARC1A_HUMAN; Arc40; ARPC1A; Epididymis luminal protein 68; Epididymis secretory protein Li 307; HEL 68; HEL S 307; SOP2-like protein; SOP2Hs; SOP2L

Target Background

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.