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The antibody against ARPC1B was raised in rabbit using the Recombinant Human Actin-related protein 2/3 complex subunit 1B protein (16-316AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against ARPC1B was raised in rabbit using the Recombinant Human Actin-related protein 2/3 complex subunit 1B protein (16-316AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using ARPC1B Antibody at dilution of 1:100
| Cat.No | ADC-11280A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARPC1B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Actin-related protein 2/3 complex subunit 1B protein (16-316AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15143 |
Uniprot Id
O15143
Target Species
Human
Target Name
ARPC1B
Target Full Name
Actin-related protein 2/3 complex subunit 1B
Target Function
Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Target Subcellular Location
Cytoplasm, cytoskeleton. Nucleus.
Target Protein Families
WD repeat ARPC1 family
Target Synonyms
Actin related protein 2/3 complex subunit 1B 41kDa ; Actin related protein 2/3 complex subunit 1B; Actin-related protein 2/3 complex subunit 1B; ARC1B_HUMAN; ARC41; Arp2/3 complex 41 kDa subunit; ARP2/3 protein complex subunit p41 ; Arpc1b; p40 ARC; p41 ARC; p41-Arc
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