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The antibody against ARPP19 was raised in rabbit using the Recombinant Human cAMP-regulated phosphoprotein 19 protein (2-105AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ARPP19 was raised in rabbit using the Recombinant Human cAMP-regulated phosphoprotein 19 protein (2-105AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human placenta tissue using ARPP19 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using ARPP19 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-13824A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARPP19 |
| Target Synonyms | ARP19 antibody; ARP19_HUMAN antibody; ARPP-19 antibody; Arpp19 antibody; cAMP-regulated phosphoprotein 19 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human cAMP-regulated phosphoprotein 19 protein (2-105AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P56211 |
Uniprot Id
P56211
Target Species
Human
Target Name
ARPP19
Target Full Name
cAMP-regulated phosphoprotein 19
Target Function
Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. May indirectly enhance GAP-43 expression.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Endosulfine family
Target Synonyms
ARP19; ARP19_HUMAN; ARPP-19; Arpp19; cAMP-regulated phosphoprotein 19
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