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The antibody against ARRDC4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Arrdc4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against ARRDC4 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Arrdc4. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
| Cat.No | ADC-33349A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARRDC4 |
| Target Synonyms | ARRD4_HUMAN antibody; ARRDC 4 antibody; Arrdc4 antibody; Arrestin domain containing protein 4 antibody; Arrestin domain-containing protein 4 antibody; FLJ36045 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Arrdc4. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NCT1 |
Uniprot Id
Q8NCT1
Target Species
Human
Target Name
ARRDC4
Target Full Name
Arrestin domain-containing protein 4
Target Function
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates. Plays a role in endocytosis of activated G protein-coupled receptors (GPCRs) (Probable). Through an ubiquitination-dependent mechanism plays also a role in the incorporation of SLC11A2 into extracellular vesicles. May play a role in glucose uptake.
Target Subcellular Location
Early endosome. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle.
Target Protein Families
Arrestin family
Target Synonyms
ARRD4_HUMAN; ARRDC 4; Arrdc4; Arrestin domain containing protein 4; Arrestin domain-containing protein 4; FLJ36045
Target Background
Predicted to enable ubiquitin ligase-substrate adaptor activity. Acts upstream of or within positive regulation of ubiquitin-protein transferase activity. Located in endosome and plasma membrane.
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