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The antibody against ASB10 was raised in rabbit using the Recombinant Human Ankyrin repeat and SOCS box protein 10 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ASB10 was raised in rabbit using the Recombinant Human Ankyrin repeat and SOCS box protein 10 protein (1-300AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human liver cancer using ASB10 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using ASB10 Antibody at dilution of 1:1002
Immunofluorescent analysis of HepG2 cells using ASB10 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-18769A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASB10 |
| Target Synonyms | ASB10Ankyrin repeat and SOCS box protein 10 antibody; ASB-10 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ankyrin repeat and SOCS box protein 10 protein (1-300AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WXI3 |
Uniprot Id
Q8WXI3
Target Species
Human
Target Name
ASB10
Target Full Name
Ankyrin repeat and SOCS box protein 10
Target Function
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Target Involvement
Glaucoma 1, open angle, F (GLC1F)
Target Subcellular Location
Cytoplasm. Nucleus. Note=In the ciliary body, it is detected in the cytoplasm and perinuclear region of the pigmented ciliary epithelial layer. In the retina, it is detected in the nuclei of retinal ganglion cells.
Target Protein Families
Ankyrin SOCS box (ASB) family
Target Tissue Specificity
Expressed in the eye. The highest expression is observed in the iris, with moderate levels in the trabecular meshwork (TM), the lamina, and the optic nerve; slightly lower levels in the ciliary body, retina, and choroid; and very low levels in the lens.
Target Synonyms
ASB10Ankyrin repeat and SOCS box protein 10; ASB-10
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