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The antibody against ASF1A was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Asf1a. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against ASF1A was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Asf1a. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
$167.00
Western Blot analysis of Jurkat cells using Asf1a Polyclonal Antibody
| Cat.No | ADC-39277A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASF1A |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Asf1a. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y294 |
Uniprot Id
Q9Y294
Target Species
Human
Target Name
ASF1A
Target Full Name
Histone chaperone ASF1A
Target Function
Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
Target Subcellular Location
Nucleus.
Target Protein Families
ASF1 family
Target Tissue Specificity
Ubiquitously expressed.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Anti silencing function 1A; Anti-silencing function protein 1 homolog A; ASF1 anti silencing function 1 homolog A (S. cerevisiae); ASF1 anti silencing function 1 homolog A; asf1a; ASF1A_HUMAN; CCG1 interacting factor A; CCG1-interacting factor A; CGI 98; CIA; hAsf1; hAsf1a; hCIA; Histone chaperone ASF1A; HSPC146
Target Background
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing function-1 gene in yeast. The protein is a key component of a histone donor complex that functions in nucleosome assembly. It interacts with histones H3 and H4, and functions together with a chromatin assembly factor during DNA replication and repair.
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