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Rabbit anti-Human ASIC5 Polyclonal Antibody

The antibody against ASIC5 was raised in rabbit using the Recombinant Human Acid-sensing ion channel 5 protein (140-330AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-16386A

The antibody against ASIC5 was raised in rabbit using the Recombinant Human Acid-sensing ion channel 5 protein (140-330AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-16386A ClonalityPolyclonal
Host SpeciesRabbitTarget NameASIC5
Target SynonymsAcid-sensing ion channel 5 antibody; amiloride sensitive cation channel 5FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IHC
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Acid-sensing ion channel 5 protein (140-330AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NY37
Background Information
  • Uniprot Id

    Q9NY37

  • Target Species

    Human

  • Target Name

    ASIC5

  • Target Full Name

    Acid-sensing ion channel 5

  • Target Function

    Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC5 subfamily

  • Target Tissue Specificity

    Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.

  • Target Synonyms

    Acid-sensing ion channel 5; amiloride sensitive cation channel 5, intestinal; Amiloride sensitive sodium channel; Amiloride-sensitive cation channel 5; ASIC5; ASIC5_HUMAN; HINaC; Human intestine Na(+) channel; INAC

  • Target Background

    This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known.

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