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The antibody against ASIC5 was raised in rabbit using the Recombinant Human Acid-sensing ion channel 5 protein (140-330AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against ASIC5 was raised in rabbit using the Recombinant Human Acid-sensing ion channel 5 protein (140-330AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-16386A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASIC5 |
| Target Synonyms | Acid-sensing ion channel 5 antibody; amiloride sensitive cation channel 5 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Acid-sensing ion channel 5 protein (140-330AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NY37 |
Uniprot Id
Q9NY37
Target Species
Human
Target Name
ASIC5
Target Full Name
Acid-sensing ion channel 5
Target Function
Cation channel that gives rise to very low constitutive currents in the absence of activation. The activated channel exhibits selectivity for sodium, and is inhibited by amiloride.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Amiloride-sensitive sodium channel (TC 1.A.6) family, ASIC5 subfamily
Target Tissue Specificity
Detected in small intestine, duodenum and jejunum. Detected at very low levels in testis and rectum.
Target Synonyms
Acid-sensing ion channel 5; amiloride sensitive cation channel 5, intestinal; Amiloride sensitive sodium channel; Amiloride-sensitive cation channel 5; ASIC5; ASIC5_HUMAN; HINaC; Human intestine Na(+) channel; INAC
Target Background
This gene belongs to the amiloride-sensitive Na+ channel and degenerin (NaC/DEG) family, members of which have been identified in many animal species ranging from the nematode to human. The amiloride-sensitive Na(+) channel encoded by this gene is primarily expressed in the small intestine, however, its exact function is not known.
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