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The antibody against ASZ1 was raised in rabbit using the Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein (1-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ASZ1 was raised in rabbit using the Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein (1-200AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using ASZ1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer using ASZ1 Antibody at dilution of 1:1002
| Cat.No | ADC-18770A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASZ1 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 protein (1-200AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WWH4 |
Uniprot Id
Q8WWH4
Target Species
Human
Target Name
ASZ1
Target Full Name
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1
Target Function
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Expressed exclusively in the testis and ovary and at higher levels in the adult testis compared with the adult ovary.
Target Synonyms
ASZ1; ALP1; ANKL1; C7orf7; GASZAnkyrin repeat; SAM and basic leucine zipper domain-containing protein 1; Ankyrin-like protein 1; Germ cell-specific ankyrin; SAM and basic leucine zipper domain-containing protein
Target Background
Predicted to be involved in gamete generation and piRNA metabolic process. Predicted to be located in cytoplasm. Predicted to be active in pi-body.
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