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The antibody against ATF3 was raised in rabbit using the Recombinant Human Cyclic AMP-dependent transcription factor ATF-3 protein (1-181AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
The antibody against ATF3 was raised in rabbit using the Recombinant Human Cyclic AMP-dependent transcription factor ATF-3 protein (1-181AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human placenta tissue using ATF3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using ATF3 Antibody at dilution of 1:1002
| Cat.No | ADC-22216A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATF3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cyclic AMP-dependent transcription factor ATF-3 protein (1-181AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P18847 |
Uniprot Id
P18847
Target Species
Human
Target Name
ATF3
Target Full Name
Cyclic AMP-dependent transcription factor ATF-3
Target Function
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTActivates transcription presumably by sequestering inhibitory cofactors away from the promoters.
Target Subcellular Location
Nucleus.
Target Protein Families
BZIP family, ATF subfamily
Target Research Area
Cancer
Target Synonyms
Activating transcription factor 3; ATF3; ATF3_HUMAN; ATF3deltaZip2; ATF3deltaZip2c; ATF3deltaZip3; cAMP dependent transcription factor ATF3; cAMP-dependent transcription factor ATF-3; Cyclic AMP dependent transcription factor ATF3; Cyclic AMP-dependent transcription factor ATF-3
Target Background
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
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