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Rabbit anti-Human ATMIN Polyclonal Antibody

The antibody against ATMIN was raised in rabbit using the Recombinant Human ATM interactor protein (160-360AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-17186A

The antibody against ATMIN was raised in rabbit using the Recombinant Human ATM interactor protein (160-360AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-17186A ClonalityPolyclonal
Host SpeciesRabbitTarget NameATMIN
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human ATM interactor protein (160-360AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO43313
Background Information
  • Uniprot Id

    O43313

  • Target Species

    Human

  • Target Name

    ATMIN

  • Target Full Name

    ATM interactor

  • Target Function

    Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.

  • Target Subcellular Location

    Nucleus. Note=Nuclear, in discrete foci during G1 phase.

  • Target Tissue Specificity

    Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.

  • Target Synonyms

    ASCIZ; ATM INteracting protein; ATM interactor; ATM substrate CHK2-interacting zinc finger protein; ATM/ATR substrate CHEK2 interacting zinc finger protein; ATM/ATR Substrate Chk2 Interacting Zn++ finger protein; ATM/ATR substrate Chk2 interacting Zn2+ finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATMIN; ATMIN_HUMAN; DKFZp779K1455; FLJ76795; KIAA0431; Zinc finger protein 822; ZNF 822; ZNF822

  • Target Background

    Enables dynein complex binding activity. Involved in positive regulation of transcription, DNA-templated. Located in nuclear body.

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