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The antibody against ATXN10 was raised in rabbit using the Human ATXN10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ATXN10 was raised in rabbit using the Human ATXN10 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-46043A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATXN10 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human ATXN10 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBB4 |
Uniprot Id
Q9UBB4
Target Species
Human
Target Name
ATXN10
Target Full Name
Ataxin-10
Target Function
Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.
Target Involvement
Spinocerebellar ataxia 10 (SCA10)
Target Subcellular Location
Cytoplasm, perinuclear region.
Target Protein Families
Ataxin-10 family
Target Tissue Specificity
Expressed in the central nervous system.
Target Synonyms
Ataxin 10; Ataxin-10; ATX10_HUMAN; Atxn10; Brain protein E46 homolog; E46L; FLJ37990; HUMEEP; Like mouse brain protein E46; OTTHUMP00000197383; SCA10; Spinocerebellar ataxia 10; Spinocerebellar ataxia type 10 protein
Target Background
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.
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