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The antibody against AZI2 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human Nap1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against AZI2 was raised in rabbit using the Synthesized peptide derived from the N-terminal region of Human Nap1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
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Western Blot analysis of HepG2 cells using Nap1 Polyclonal Antibody
| Cat.No | ADC-38140A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AZI2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the N-terminal region of Human Nap1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H6S1 |
Uniprot Id
Q9H6S1
Target Species
Human
Target Name
AZI2
Target Full Name
5-azacytidine-induced protein 2
Target Function
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Widely expressed. Abundant expression seen in the pancreas and testis.
Target Synonyms
5 azacytidine induced protein 2; 5-azacytidine-induced protein 2; AA410145; AZ2; AZI2; AZI2_HUMAN; MGC112644; Nak associated protein 1; Nak-associated protein 1; NAP1; NF kappa B activating kinase associated protein 1; NF-kappa-B-activating kinase-associated protein 1; TILP; TILP(S)
Target Background
AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).
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