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The antibody against BAIAP3 was raised in rabbit using the Recombinant Human BAI1-associated protein 3 protein (131-257AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against BAIAP3 was raised in rabbit using the Recombinant Human BAI1-associated protein 3 protein (131-257AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-06956A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BAIAP3 |
| Target Synonyms | BAI1 associated protein 3 antibody; BAI1-associated protein 3 antibody; Baiap3 antibody; BAIP3_HUMAN antibody; BAP2 antibody; BAP3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human BAI1-associated protein 3 protein (131-257AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O94812 |
Uniprot Id
O94812
Target Species
Human
Target Name
BAIAP3
Target Full Name
BAI1-associated protein 3
Target Function
Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin. Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission.
Target Subcellular Location
Cytoplasm, cytosol. Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein.
Target Protein Families
Unc-13 family
Target Tissue Specificity
Predominantly expressed in brain. Also expressed in nonneural tissues such as breast and testes epithelium.
Target Synonyms
BAI1 associated protein 3; BAI1-associated protein 3; Baiap3; BAIP3_HUMAN; BAP2; BAP3
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