Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against BBC3 was raised in rabbit using the Peptide sequence from Human Bcl-2-binding component 3 protein (5-23AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against BBC3 was raised in rabbit using the Peptide sequence from Human Bcl-2-binding component 3 protein (5-23AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
Western Blot_x000D_ | Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, 293T whole cell lysate, U87 whole cell lysate, Rat kidney tissue_x000D_ | All lanes: BBC3 antibody at 1:2000_x000D_ | Secondary_x000D_ | Goat polyclonal to rabbit IgG at 1/50000 dilution_x000D_ | Predicted band size: 21, 15 kDa_x000D_ | Observed band size: 21 kDa
| Cat.No | ADC-01412A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BBC3 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence from Human Bcl-2-binding component 3 protein (5-23AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BXH1 |
Uniprot Id
Q9BXH1
Target Species
Human
Target Name
BBC3
Target Full Name
Bcl-2-binding component 3, isoforms 1/2
Target Function
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Target Subcellular Location
Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
Target Protein Families
Bcl-2 family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
BBC 3; Bbc3; BBC3_HUMAN; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
