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The antibody against BBC3 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PUMA. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against BBC3 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human PUMA. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of 293 cells using PUMA Polyclonal Antibody
| Cat.No | ADC-37771A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BBC3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human PUMA. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BXH1 |
Uniprot Id
Q9BXH1
Target Species
Human
Target Name
BBC3
Target Full Name
Bcl-2-binding component 3, isoforms 1/2
Target Function
Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Target Subcellular Location
Mitochondrion. Note=Localized to the mitochondria in order to induce cytochrome c release.
Target Protein Families
Bcl-2 family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
BBC 3; Bbc3; BBC3_HUMAN; BCL 2 binding component 3; Bcl-2-binding component 3; BCL2 binding component 3; JFY 1; JFY-1; JFY1; p53 up regulated modulator of apoptosis; p53 up-regulated modulator of apoptosis; p53 Upregulated Modulator of Apoptosis; PUMA alpha; PUMA/JFY1
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