Rabbit anti-Human BCAS2 Polyclonal Antibody

The antibody against BCAS2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-09756A

Number

Cat.No	ADA-09756A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	BCAS2
Target Synonyms	DAM1; SPF27; Snt309; BCAS2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T, Jurkat, MCF-7, Mouse lung, Mouse spleen, Mouse testis, Rat lung, SKOV3	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-09756A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

BCAS2

Target Synonyms

DAM1; SPF27; Snt309; BCAS2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T, Jurkat, MCF-7, Mouse lung, Mouse spleen, Mouse testis, Rat lung, SKOV3

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1).	Target Species	Human
Uniprot ID	O75934	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human BCAS2 (NP_005863.1).

Target Species

Human

Uniprot ID

O75934

Immunogen Sequence

Background Information

Uniprot Id

O75934
Target Species

Human
Target Name

BCAS2
Target Full Name

Pre-mRNA-splicing factor SPF27
Target Function

Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Target Subcellular Location

Nucleus. Nucleus, nucleolus.
Target Protein Families

SPF27 family
Target Tissue Specificity

Ubiquitously expressed.
Target Research Area

Tags & Cell Markers
Target Synonyms

bcas2; Breast carcinoma amplified sequence 2; Breast carcinoma-amplified sequence 2; DAM 1; DAM-1; DAM1; DNA amplified in mammary carcinoma 1 protein; MGC7712; Pre mRNA splicing factor SPF27; Pre-mRNA-splicing factor spf27; Snt309; SPF27; SPF27_HUMAN; Spliceosome associated protein amplified in breast cancer; Spliceosome associated protein SPF 27; Spliceosome-associated protein SPF 27
Target Background

Involved in mRNA splicing, via spliceosome. Located in centrosome and nuclear speck. Part of U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex. Implicated in breast cancer.

Rabbit anti-Human BCAS2 Polyclonal Antibody

Specifications

Immunogen Information

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