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The antibody against BCHE was raised in rabbit using the Recombinant Human Cholinesterase protein (311-524AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against BCHE was raised in rabbit using the Recombinant Human Cholinesterase protein (311-524AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-09764A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BCHE |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cholinesterase protein (311-524AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P06276 |
Uniprot Id
P06276
Target Species
Human
Target Name
BCHE
Target Full Name
Cholinesterase
Target Function
Esterase with broad substrate specificity. Contributes to the inactivation of the neurotransmitter acetylcholine. Can degrade neurotoxic organophosphate esters.
Target Involvement
Butyrylcholinesterase deficiency (BChE deficiency)
Target Subcellular Location
Secreted.
Target Protein Families
Type-B carboxylesterase/lipase family
Target Tissue Specificity
Detected in blood plasma (at protein level). Present in most cells except erythrocytes.
Target Research Area
Neuroscience
Target Synonyms
Acylcholine acylhydrolase; BCHE; Butyrylcholine esterase; CHE1; CHE2; CHLE_HUMAN; Choline esterase II; Cholinesterase (serum) 2; Cholinesterase 1; Cholinesterase; E1; Pseudocholinesterase; Pseudocholinesterase E1
Target Background
This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine.
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