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The antibody against BCL2L12 was raised in rabbit using the Fusion protein of Human BCL2L12 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against BCL2L12 was raised in rabbit using the Fusion protein of Human BCL2L12 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-32409A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BCL2L12 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human BCL2L12 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HB09 |
Uniprot Id
Q9HB09
Target Species
Human
Target Name
BCL2L12
Target Full Name
Bcl-2-like protein 12
Target Synonyms
B2L12_HUMAN; BCL 2 like 12 (proline rich); BCL 2 like 12; BCL 2 like 12 isoform 1; Bcl 2 like 12 protein; Bcl 2 related proline rich protein; Bcl-2-like protein 12; Bcl-2-related proline-rich protein; BCL2 like 12 (proline rich); BCL2 like 12; BCL2 like 12 isoform 1; Bcl2 like 12 protein; Bcl2 related proline rich protein; Bcl2-L-12; BCL2L12; BPR; MGC120313; MGC120314; MGC120315
Target Background
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
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