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The antibody against BCOR was raised in rabbit using the Fusion protein of Human BCOR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against BCOR was raised in rabbit using the Fusion protein of Human BCOR as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-32414A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BCOR |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human BCOR | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6W2J9 |
Uniprot Id
Q6W2J9
Target Species
Human
Target Name
BCOR
Target Full Name
BCL-6 corepressor
Target Function
Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells; the function implies inhibition of methylation on histone H3 'Lys-4' (H3K4me3) and 'Lys-36' (H3K36me2).
Target Involvement
Microphthalmia, syndromic, 2 (MCOPS2)
Target Subcellular Location
Nucleus.
Target Protein Families
BCOR family
Target Tissue Specificity
Ubiquitously expressed.
Target Synonyms
5830466J11Rik; 8430401K06Rik; ANOP 2; ANOP2; BCL 6 co repressor; BCL 6 corepressor; BCL 6 interacting corepressor; BCL-6 corepressor; BCL6 co repressor; BCL6 corepressor; BCL6 interacting corepressor; BCoR; BCOR_HUMAN; FLJ20285; FLJ38041; KIAA1575; MAA 2; MAA2; MCOPS 2; MCOPS2; MGC131961; MGC71031
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