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Rabbit anti-Human BHLHA15 Polyclonal Antibody

The antibody against BHLHA15 was raised in rabbit using the Recombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-03263A

The antibody against BHLHA15 was raised in rabbit using the Recombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-03263A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBHLHA15
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Class A basic helix-loop-helix protein 15 protein (2-72AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ7RTS1
Background Information
  • Uniprot Id

    Q7RTS1

  • Target Species

    Human

  • Target Name

    BHLHA15

  • Target Full Name

    Class A basic helix-loop-helix protein 15

  • Target Function

    Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Expressed in brain, liver, spleen and skeletal muscle.

  • Target Synonyms

    Basic helix loop helix domain containing class B 8; Basic helix loop helix family member a15; BHA15_HUMAN; Bhlha15; bHLHB8; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; Class II bHLH protein MIST1; intestine and stomach expression 1; MIST 1; MIST-1; MIST1; Muscle; Muscle intestine and stomach expression 1; protein MIST1

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