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The antibody against BIN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human BIN3 (NP_061158.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against BIN3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human BIN3 (NP_061158.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05027A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BIN3 |
| Target Synonyms | BIN3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, A-549, A431, Mouse spleen, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-253 of human BIN3 (NP_061158.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9NQY0 | Immunogen Sequence |
Uniprot Id
Q9NQY0
Target Species
Human
Target Name
BIN3
Target Full Name
Bridging integrator 3
Target Function
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Tissue Specificity
Ubiquitously expressed except in brain.
Target Synonyms
BIN3Bridging integrator 3
Target Background
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
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