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The antibody against BIN3 was raised in rabbit using the Recombinant Human Bridging integrator 3 protein (8-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against BIN3 was raised in rabbit using the Recombinant Human Bridging integrator 3 protein (8-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
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Immunofluorescent analysis of A549 cells using BIN3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
| Cat.No | ADC-09763A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BIN3 |
| Target Synonyms | BIN3Bridging integrator 3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bridging integrator 3 protein (8-240AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NQY0 |
Uniprot Id
Q9NQY0
Target Species
Human
Target Name
BIN3
Target Full Name
Bridging integrator 3
Target Function
Involved in cytokinesis and septation where it has a role in the localization of F-actin.
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Tissue Specificity
Ubiquitously expressed except in brain.
Target Synonyms
BIN3Bridging integrator 3
Target Background
The product of this gene is a member of the BAR domain protein family. The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization, sense and induce membrane curvature, and bind small GTPases. BAR domain proteins have been implicated in endocytosis, intracellular transport, and a diverse set of other processes.
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