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The antibody against BLOC1S5 was raised in rabbit using the Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 5 protein (2-187AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against BLOC1S5 was raised in rabbit using the Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 5 protein (2-187AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human prostate cancer using BLOC1S5 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human melanoma using BLOC1S5 Antibody at dilution of 1:1002
| Cat.No | ADC-18947A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BLOC1S5 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 5 protein (2-187AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TDH9 |
Uniprot Id
Q8TDH9
Target Species
Human
Target Name
BLOC1S5
Target Full Name
Biogenesis of lysosome-related organelles complex 1 subunit 5
Target Function
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking.
Target Protein Families
BLOC1S5 family
Target Synonyms
Biogenesis of lysosomal organelles complex 1; subunit 5; muted; Biogenesis of lysosome related organelles complex 1 subunit 5; BLOC 1 subunit 5; BLOC1S5; BLOS5; MU; MUTED; Muted homolog; Muted protein homolog; MUTED_HUMAN; Protein Muted homolog
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