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The antibody against BLVRA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against BLVRA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09791A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BLVRA |
| Target Synonyms | BVR; BLVR; BVRA; BLVRA | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-296 of human BLVRA (NP_001240752.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P53004 | Immunogen Sequence |
Uniprot Id
P53004
Target Species
Human
Target Name
BLVRA
Target Full Name
Biliverdin reductase A
Target Function
Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
Target Involvement
Hyperbiliverdinemia (HBLVD)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Gfo/Idh/MocA family, Biliverdin reductase subfamily
Target Tissue Specificity
Liver.
Target Research Area
Signal Transduction
Target Synonyms
BIEA_HUMAN; Biliverdin IX alpha reductase; Biliverdin reductase A; Biliverdin-IX alpha-reductase; BLVR A; BLVR; Blvra; BVR A; BVR; BVRA; Zinc metalloprotein
Target Background
The protein encoded by this gene belongs to the biliverdin reductase family, members of which catalyze the conversion of biliverdin to bilirubin in the presence of NADPH or NADH. Mutations in this gene are associated with hyperbiliverdinemia. Alternatively spliced transcript variants have been found for this gene.
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