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The antibody against BMF was raised in rabbit using the Recombinant Human Bcl-2-modifying factor protein (1-184AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against BMF was raised in rabbit using the Recombinant Human Bcl-2-modifying factor protein (1-184AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver cancer using BMF Antibody at dilution of 1:100
| Cat.No | ADC-45161A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BMF |
| Target Synonyms | Bcl 2 modifying factor antibody; Bcl-2-modifying factor antibody; Bcl2 modifying factor antibody; Bmf antibody; BMF_HUMAN antibody; FLJ00065 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bcl-2-modifying factor protein (1-184AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96LC9 |
Uniprot Id
Q96LC9
Target Species
Human
Target Name
BMF
Target Full Name
Bcl-2-modifying factor
Target Function
May play a role in apoptosis. Isoform 1 seems to be the main initiator.
Target Protein Families
Bcl-2 family
Target Tissue Specificity
Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.
Target Research Area
Cell Biology
Target Synonyms
Bcl 2 modifying factor; Bcl-2-modifying factor; Bcl2 modifying factor; Bmf; BMF_HUMAN; FLJ00065
Target Background
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. This protein is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular damage and triggering apoptosis. Alternatively spliced transcript variants encoding different isoforms have been identified.
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