Rabbit anti-Human BMP15 Monoclonal Antibody

The antibody against BMP15 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 293-392 of human BMP15 (O95972) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13870A

Number

Cat.No	ADA-13870A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	BMP15
Target Synonyms	ODG2; POF4; GDF9B; BMP15	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, A-431, Mouse lung, Mouse ovary, Rat ovary, SKOV3	Application	ELISA, WB

Cat.No

ADA-13870A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

BMP15

Target Synonyms

ODG2; POF4; GDF9B; BMP15

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, A-431, Mouse lung, Mouse ovary, Rat ovary, SKOV3

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 293-392 of human BMP15 (O95972).	Target Species	Human
Immunogen Sequence	LHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR	Uniprot ID	O95972

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 293-392 of human BMP15 (O95972).

Target Species

Human

Immunogen Sequence

LHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLINQLVDQSVPRPSCVPYKYVPISVLMIEANGSILYKEYEGMIAESCTCR

Uniprot ID

O95972

Background Information

Uniprot Id

O95972
Target Species

Human
Target Name

BMP15
Target Full Name

Bone morphogenetic protein 15
Target Function

May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
Target Involvement

Ovarian dysgenesis 2 (ODG2); Premature ovarian failure 4 (POF4)
Target Subcellular Location

Secreted.
Target Protein Families

TGF-beta family
Target Research Area

Developmental Biology
Target Synonyms

BMP 15; BMP-15; BMP15; BMP15_HUMAN; Bone morphogenetic protein 15; GDF 9B; GDF-9B; GDF9B; Growth/differentiation factor 9B; ODG2 ; POF4
Target Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure.

Rabbit anti-Human BMP15 Monoclonal Antibody

Specifications

Immunogen Information

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