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The antibody against BPI was raised in rabbit using the Recombinant Human Bactericidal permeability-increasing protein (149-362AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
The antibody against BPI was raised in rabbit using the Recombinant Human Bactericidal permeability-increasing protein (149-362AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IF.
$299.00
| Cat.No | ADC-13624A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BPI |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Bactericidal permeability-increasing protein (149-362AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P17213 |
Uniprot Id
P17213
Target Species
Human
Target Name
BPI
Target Full Name
Bactericidal permeability-increasing protein
Target Function
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Target Subcellular Location
Secreted. Cytoplasmic granule membrane.
Target Protein Families
BPI/LBP/Plunc superfamily, BPI/LBP family
Target Tissue Specificity
Restricted to cells of the myeloid series.
Target Research Area
Immunology
Target Synonyms
Bactericidal permeability-increasing protein; Bactericidal/permeability increasing protein; BPI; BPI fold containing family D; member 1; BPI_HUMAN; BPIFD1; CAP 57; CAP57; rBPI; Recombinant BPI holoprotein; rBPI
Target Background
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has antimicrobial activity against gram-negative organisms.
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