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The antibody against BPI was raised in rabbit using the Fusion protein of Human BPI as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against BPI was raised in rabbit using the Fusion protein of Human BPI as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-30494A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BPI |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human BPI | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P17213 |
Uniprot Id
P17213
Target Species
Human
Target Name
BPI
Target Full Name
Bactericidal permeability-increasing protein
Target Function
The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa.
Target Subcellular Location
Secreted. Cytoplasmic granule membrane.
Target Protein Families
BPI/LBP/Plunc superfamily, BPI/LBP family
Target Tissue Specificity
Restricted to cells of the myeloid series.
Target Research Area
Immunology
Target Synonyms
Bactericidal permeability-increasing protein; Bactericidal/permeability increasing protein; BPI; BPI fold containing family D; member 1; BPI_HUMAN; BPIFD1; CAP 57; CAP57; rBPI; Recombinant BPI holoprotein; rBPI
Target Background
This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has antimicrobial activity against gram-negative organisms.
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